AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |
Back to Blog
Shark ip10/30/2023 ![]() MY COBRA IPTV provide tow Edition for you Shark iptv strong stable 100, don’t lose your time looking other side, grab you edition and. These results indicate a possible role for the use of 5beta-scymnol, either alone or concomitant with NAC, in the prevention of hepatic necrosis following toxic doses of APAP. Shark IPTV is The most powerful IPTV provider in the market, where we use the latest technologies and top servers to provide you with a service of optimal quality to follow your favorite programs quickly. In addition, 5beta-scymnol has potent hydroxyl radical quenching activity as it markedly inhibited deoxyribose degradation in a ferrous/ascorbate Fenton reaction system. Coadministration of 5beta-scymnol (70 mg/kg) and NAC (250 mg/kg) also reduced serum enzyme levels and histopathological effects however, a similar level of hepatoprotection was conferred by 5beta-scymnol treatment alone. N-Acetylcysteine (NAC) is protective against APAP-induced hepatotoxicity at 250 and 500 mg/kg (ip) when administered up to 3 hr after APAP overdose, as shown by a significant reduction in serum enzyme activity. The highest dose of 5beta-scymnol remained hepatoprotective when administered 4 hr after the APAP overdose. 5beta-Scymnol at doses of 20, 35, and 70 mg/kg intraperitoneally (ip) decreased significantly the serum activity of alanine aminotransferase, sorbitol dehydrogenase, and lactate dehydrogenase (p < 0.05) caused by APAP treatment (350 mg/kg ip) alone. The hepatoprotective effect of the shark bile salt 5beta-scymnol has been studied in the model of acute hepatotoxicity induced by administration of acetaminophen (APAP, paracetamol). ![]()
0 Comments
Read More
Leave a Reply. |